Browsing by Author "Turgut, Nergiz Hacer"
Now showing items 1-13 of 13
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Anticancer Effect of COX-2 Inhibitor DuP-697 Alone and in Combination with Tyrosine Kinase Inhibitor (E7080) on Colon Cancer Cell Lines
Altun, Ahmet; Turgut, Nergiz Hacer; Kaya, Tijen Temiz (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)Colorectal cancer remains one of the most common types of cancer and a leading cause of cancer death worldwide. In this study, we aimed to investigate effects of DuP-697, an irreversible selective inhibitor of COX-2 on ... -
Effect of black mulberry (Morus nigra) extract treatment on cognitive impairment and oxidative stress status of d-galactose-induced aging mice
Turgut, Nergiz Hacer; Mert, Derya Guliz; Kara, Haki; Egilmez, Hatice Reyhan; Arslanbas, Emre; Tepe, Bektas; Gungor, Huseyin; Yilmaz, Nese; Tuncel, Necati Baris (TAYLOR & FRANCIS LTD, 2016)Context: Morus nigra L. (Moraceae) has various uses in traditional medicine. However, the effect of M. nigra on cognitive impairment has not been investigated yet. Objective: The objective of this study is to determine the ... -
Effect of Capparis spinosa L. on cognitive impairment induced by D-galactose in mice via inhibition of oxidative stress
Turgut, Nergiz Hacer; Kara, Haki; Arslanbas, Emre; Mert, Derya Guliz; Tepe, Bektas; Gungor, Huseyin (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2015)Background/aim: To determine the phenolic acid levels and DNA damage protection potential of Capparis spinosa L. seed extract and to investigate the effect of the extract on cognitive impairment and oxidative stress in an ... -
The effect of octreotide, an analog of somatostatin, on bleomycin-induced interstitial pulmonary fibrosis in rats
Tug, Tuncer; Kara, Haki; Karaoglu, Aziz; Karatas, Fikret; Turgut, Nergiz Hacer; Ayan, Erhan; Boran, Cetin; Tug, Esra (TAYLOR & FRANCIS LTD, 2013)In this study, octreotide (OCT), a synthetic sonnatostatin analog, was tested for its beneficial effects in the prevention of interstitial pulmonary fibrosis (IPF) induced by bleomycin (BLM) in rats by histological examination ... -
The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat pre-eclampsia model
Turgut, Nergiz Hacer; Temiz, Tijen Kaya; Bagcivan, Ihsan; Turgut, Butent; Gulturk, Sefa; Karadas, Baris (ELSEVIER SCIENCE BV, 2008)The pathophysiology of pre-eclampsia is still unknown thus effective primary prevention is not possible at the stage. The present study was conducted to research the smooth muscle responses in the pre-eclampsia model with ... -
Evaluation of myocardial viability with thallium-201 infusion MPSPECT after oral glucose application in patients with chronic coronary artery disease
Hasbek, Zekiye; Turgut, Bulent; Erselcan, Janer; Yalta, Kenan; Tandogan, Izzet; Ozer, Gurkan; Ozdemir, Umit; Turgut, Nergiz Hacer (LIPPINCOTT WILLIAMS & WILKINS, 2009)Aim The aim of this study was to evaluate the myocardial viability in nondiabetic patients with chronic coronary artery disease (CCAD) or past myocardial infarction (MI), using thallium-201 infusion myocardial perfusion ... -
Histopathological evaluation of the effect of locally administered strontium on healing time in mandibular fractures: An experimental study
Durmus, Kasim; Turgut, Nergiz Hacer; Dogan, Mehtap; Tuncer, Ersin; Ozer, Hatice; Altuntas, Emine Elif; Akyol, Melih (WROCLAW MEDICAL UNIV, 2017)Background. Mandibular fractures are the most common facial fractures. They can be treated by conservative techniques or by surgery. The authors hypothesized that the application of a single local dose of strontium chloride ... -
The influence of quercetin on recognition memory and brain oxidative damage in a ketamine model of schizophrenia
Mert, Derya Guliz; Turgut, Nergiz Hacer; Arslanbas, Emre; Gungor, Huseyin; Kara, Haki (TAYLOR & FRANCIS LTD, 2019)OBJECTIVE: The aims of this study were to investigate the protective effect of quercetin on changes in recognition memory as assessed by the novel object recognition (NOR) test, as well as on changes in the oxidative stress ... -
Investigation of the role of the NO-cGMP pathway on YC-1 and DEA/NO effects on thoracic aorta smooth muscle responses in a rat preeclampsia model
Turgut, Nergiz Hacer; Temiz, Tijen Kaya; Turgut, Bulent; Karadas, Baris; Parlak, Mesut; Bagcivan, Ihsan (CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2013)The present study was designed to investigate the effects of YC-1, a nitric oxide (NO)-independent soluble guanylate cyclase (sGC) activator, and DEA/NO, a NO donor, on smooth muscle responses in the preeclampsia model ... -
Perspectives on reasons of medication nonadherence in psychiatric patients
Mert, Derya Guliz; Turgut, Nergiz Hacer; Kelleci, Meral; Semiz, Murat (DOVE MEDICAL PRESS LTD, 2015)Purpose: This study was carried out to evaluate factors resulting in medication nonadherence within 6 months before admission to the psychiatric service of our hospital for bipolar disorder, schizophrenia/schizoaffective ... -
The seroprevalence of Anaplasma phagocytophilum in humans from two different climatic regions of Turkey and its co-seroprevalence rate with Borrelia burgdorferi
Gunes, Turabi; Poyraz, Omer; Atas, Mehmet; Turgut, Nergiz Hacer (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2011)Aim: To investigate the seroprevalence of Anaplasma phagocytophilum in people living in 2 different climatic regions and to evaluate the co-seroprevalence rate of A. phagocytophilum with Borrelia burgdorferi. Sinop and ... -
The seroprevalence of Rickettsia conorii in humans living in villages of Tokat Province in Turkey, where Crimean-Congo hemorrhagic fever virus is endemic, and epidemiological similarities of both infectious agents
Gunes, Turabi; Poyraz, Omer; Atas, Mehmet; Turgut, Nergiz Hacer (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2012)Aim: Tokat Province is an epicenter for Crimean-Congo hemorrhagic fever virus (CCHFV) in Turkey. The aim of this study was to investigate the seroprevalence of Rickettsia conorii and to clarify the epidemiological similarities ... -
Strontium chloride hexahydrate as a candidate molecule for long-term treatment of allergic rhinitis
Altuntas, Emine Elif; Turgut, Nergiz Hacer; Durmus, Kasim; Dogan, Omer Tamer; Akyol, Melih (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2017)Background & objectives: Neurogenic inflammation plays a role in the pathophysiology of allergic rhinitis (AR). Strontium salts are highly effective in reducing the sensory irritation. This study was aimed to investigate ...